Researchers have developed strategies to identify regulators of intestinal hormone secretion. In response to incoming food, these hormones are secreted by rare hormone producing cells in the gut and play key roles in managing digestion and appetite. The team has developed new tools to identify potential 'nutrient sensors' on these hormone producing cells and study their function. This could result in new strategies to interfere with the release of these hormones and provide avenues for the treatment of a variety of metabolic or gut motility disorders.
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