What we can learn from hungry yeast cells

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and at University of Virginia School of Medicine have revealed a new cellular adaptation to starvation, in which the mitochondria of yeast cells get coated by ribosomes. Surprisingly, the ribosomes attach to the mitochondrial outer membrane with a very unusual 'upside-down' orientation. The discovery of this mechanism has potential implications for our understanding of how stressed cancer cells survive starvation.

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and at University of Virginia School of Medicine have revealed a new cellular adaptation to starvation, in which the mitochondria of yeast cells get coated by ribosomes. Surprisingly, the ribosomes attach to the mitochondrial outer membrane with a very unusual 'upside-down' orientation. The discovery of this mechanism has potential implications for our understanding of how stressed cancer cells survive starvation.

Read more https://www.sciencedaily.com/releases/2024/10/241008122552.htm