Patients with unexplainable chronic itch have unique blood biomarkers that could eventually lead to new targeted treatments

Millions of patients worldwide suffer from a chronic itching condition with no identifiable cause -- a condition known as chronic pruritus of unknown origin (CPUO) -- that has no targeted therapies approved to treat it. Many of these patients suffer for years with little relief, but a new study may provide hope for future treatments. Patients were found to have lower than normal levels of metabolite biomarkers in the blood plasma that could point to a cause of their excruciating symptoms.

Millions of patients worldwide suffer from a chronic itching condition with no identifiable cause -- a condition known as chronic pruritus of unknown origin (CPUO) -- that has no targeted therapies approved to treat it. Many of these patients suffer for years with little relief, but a new study may provide hope for future treatments. Patients were found to have lower than normal levels of metabolite biomarkers in the blood plasma that could point to a cause of their excruciating symptoms.

Read more https://www.sciencedaily.com/releases/2024/08/240814170330.htm