A new tuberculosis vaccine candidate recombinant protein with additional post-translational modifications occurring in Mycobacterium tuberculosis cells

Tuberculosis is a serious health threat, and the efficacy of the BCG vaccine against tuberculosis diminishes in adulthood, making booster vaccines a realistic option. Mycobacterial DNA-binding protein 1 (MDP1), a protein found in Mycobacterium tuberculosis, elicits higher protective IFN-gamma responses in individuals who suppress tuberculosis, thus making it a vaccine candidate.

Tuberculosis is a serious health threat, and the efficacy of the BCG vaccine against tuberculosis diminishes in adulthood, making booster vaccines a realistic option. Mycobacterial DNA-binding protein 1 (MDP1), a protein found in Mycobacterium tuberculosis, elicits higher protective IFN-gamma responses in individuals who suppress tuberculosis, thus making it a vaccine candidate.

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