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What’s in your wallet -- Capital One
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You’re in good hands -- Allstate
The ultimate driving machine -- BMW

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The Power of Truth^®

Wednesday, November 13, 2024

Promising drug target for treating osteoporosis

Health

Osteoporosis or the weakening of bones makes the aging population vulnerable to fractures and a decreased quality of life. The parathyroid hormone (PTH)-derived peptide -- teriparatide has demonstrated strong bone promoting effects. However, it is also to known to exert bone-resorbing effects. A new study uncovers a novel PTH-inducible target gene -- Gprc5a which suppresses the proliferation and differentiation of 'osteoblasts' or bone-forming cells, and may serve as a therapeutic target in the treatment of osteoporosis.

Osteoporosis or the weakening of bones makes the aging population vulnerable to fractures and a decreased quality of life. The parathyroid hormone (PTH)-derived peptide -- teriparatide has demonstrated strong bone promoting effects. However, it is also to known to exert bone-resorbing effects. A new study uncovers a novel PTH-inducible target gene -- Gprc5a which suppresses the proliferation and differentiation of 'osteoblasts' or bone-forming cells, and may serve as a therapeutic target in the treatment of osteoporosis.

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